Sa1169 – Gerd Symptoms Exacerbation After Ppi Discontinuation May Not Be Related to Increased Esophageal Acid Exposure. the “Reverse Ppi” Test Does Not Distinguish True Gerd from Functional Symptoms
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چکیده
منابع مشابه
Patients with refractory reflux symptoms often do not have GERD.
BACKGROUND In patients with typical reflux symptoms that persist despite proton pump inhibitors (PPIs) it is sometimes overlooked that treatment fails due to the presence of other disorders than gastroesophageal reflux disease (GERD). The aim of this study was to determine the underlying cause of reflux symptoms not responding to PPI therapy in tertiary referral patients. METHODS Patients wit...
متن کاملGastroesophageal reflux disease-related symptom recurrence in patients discontinuing proton pump inhibitors for Bravo® wireless esophageal pH monitoring study.
BACKGROUND Patients with gastroesophageal reflux disease (GERD) are treated with proton pump inhibitors (PPIs). Those that do not achieve symptom relief, or non-responders, usually undergo esophageal pH monitoring off PPIs in order to confirm the presence of GERD. AIMS To assess the efficacy of the reverse-PPI trial in evaluating the presence of GERD or its recurrence rates, as well as to ide...
متن کاملLaryngopharyngeal reflux--it's not GERD.
Laryngopharyngeal reflux (LPR) and gastro-esophageal reflux disease (GERD) are different disorders. The term LPR is used to describe the acid in the stomach that comes up into the throat at the level of the laryngopharnyx. LPR causes irritation and changes in the larynx. GERD is cause by the backflow of gastric contents into the esophagus, which leads to tissue damage or esophagitis and heartburn.
متن کاملProton Pump Inhibitor-Responsive Esophageal Eosinophilia: Controversies and Its Clinical Implications
The definition of esophageal eosinophilia has changed over the past years. Before 1980s, esophageal eosinophilia had been merely regarded as a manifestation of gastroesophageal reflux disease (GERD). Since the mid-1990s, there have been numerous studies that reported esophageal eosinophilia with symptoms other than GERD, characterized by esophageal motility disorders and/or food intolerance, bo...
متن کاملGERD assessment including pH metry predicts a high response rate to PPI standard therapy
BACKGROUND Inadequate response to proton pump inhibitor (PPI) therapy in patients with gastroesophageal reflux disease (GERD) is reported in up to 40%. Patients with non erosive reflux disease (NERD) have lower response rates compared to patients with erosive reflux disease (ERD); pH metry contributes to GERD diagnosis and is critical for proper diagnosis of NERD. Aim of the study was to assess...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2019
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)37551-1